Cooking pork tenderloin in the oven at 350 degrees can be a delicious way to prepare a meal. Not only is it flavorful, but with some careful preparation and formulating the right cooking plan, you can get your pork tenderloin cooked perfectly every time. But how long should you cook that delicious cut of meat mix? This post will guide you through the process of finding out just how long to cook pork tenderloin in oven at 350 for perfect cooking results.
Contents
- 1 What Is Pork Tenderloin?
- 2 What’s the Difference Between Pork Loin and Pork Tenderloin?
- 3 What Temperature Should I Cook A Pork Tenderloin At?
- 4 How To Prepare To Cook Pork Tenderloin Perfectly?
- 5 How Long To Cook Pork Tenderloin In Oven At 350?
- 6 What Affect The Time To Cook Pork Tenderloin In Oven At 350?
- 7 What Do You Need to Cook Pork Tenderloin in the Oven at 350?
- 8 How To Cook Pork Tenderloin In Oven At 350?
- 9 How Do You Know When Pork Tenderloin Is Done?
- 10 What To Serve With Baked Pork Tenderloin?
- 11 How To Store Oven-Baked Pork Tenderloin?
- 12 Oven-Baked Pork Tenderloin Recipes
- 13 Conclusion: How Long To Cook Pork Tenderloin In Oven At 350?
- 14 FAQ: Pork Tenderloin
- 14.1 What is the best temperature to cook pork tenderloin?
- 14.2 Is it better to cook pork tenderloin fast or slow?
- 14.3 Should pork tenderloin be baked covered or uncovered?
- 14.4 Can I cook a pork tenderloin at 200 degrees?
- 14.5 What is the best method of cooking pork tenderloin?
- 14.6 What temperature should pork tenderloin be cooked to in Celsius?
- 14.7 How long does pork tenderloin take to cook at 225?
- 14.8 How long does it take to cook a pork tenderloin?
- 14.9 Does pork tenderloin get softer the longer it cooks?
- 14.10 Should you rinse pork tenderloin before cooking?
- 14.11 Can pork tenderloin be cooked at 350?
What Is Pork Tenderloin?
Pork tenderloin is a cut of meat from the loin muscle of a pig. It’s an extremely lean, tender, and flavorful cut of pork that can be cooked in many different ways.

What’s the Difference Between Pork Loin and Pork Tenderloin?
Pork loin and pork tenderloin are two different cuts of meat from the same animal. Pork loin is a long cut of meat that runs along both sides of a pig’s spine, while pork tenderloin is much smaller, thinner, and more delicate.
What Temperature Should I Cook A Pork Tenderloin At?
When it comes to how long to cook a pork tenderloin in the oven at 350 degrees, the best temperature is between 325 and 375. At 350 degrees, you should plan to bake your pork tenderloin for approximately 25 minutes per pound.
How To Prepare To Cook Pork Tenderloin Perfectly?
- Cut off the silver skin: The first step is to cut off the silver skin. This can be done with a sharp knife and requires some patience.
- Brine the pork tenderloin: Once the silver skin is removed, you can submerge your pork tenderloin in a brine made of salt, sugar, and water. This will help lock in moisture and add flavor.
- Sear the pork tenderloin: Next, heat a skillet on medium-high heat and add 2 tablespoons of olive oil or butter to it.
- Make sure the cut is even: Before you roast your pork tenderloin, make sure the cut is even. This will help ensure that it cooks evenly and prevents drying out.

How Long To Cook Pork Tenderloin In Oven At 350?
When baking a pork tenderloin in the oven at 350 degrees, it’s typically recommended that you bake it for 25 minutes per pound. For example, if your pork tenderloin weighs 1 pound, you would need to bake it for 25 minutes. If your pork tenderloin is 2 pounds, then you would need to cook it for 50 minutes.
It’s important to note that the internal temperature of the pork should reach 145 degrees Fahrenheit before you can safely eat it. To get an accurate reading of your meat’s internal temperature, we recommend using a digital thermometer.
How Long To Cook A 2 lb Pork Tenderloin In Oven At 350?
If your pork tenderloin weighs 2 pounds, you would need to cook it for 50 minutes at 350 degrees. Again, the internal temperature of your pork should reach 145 degrees Fahrenheit before you can safely eat it.
What Affect The Time To Cook Pork Tenderloin In Oven At 350?
When cooking a pork tenderloin in the oven at 350 degrees, there are several factors that can affect how long you need to cook it. These include:
- The size and weight of your pork tenderloin
- The temperature of the oven (it should be between 325 and 375 degrees)
- Whether or not you brine the pork before cooking
- Whether or not you sear the pork before baking
By taking all of these factors into consideration, you can ensure that your pork tenderloin is perfectly cooked every time.

What Do You Need to Cook Pork Tenderloin in the Oven at 350?
To cook a pork tenderloin in the oven at 350 degrees, you’ll need:
- Pork tenderloin
- Olive oil
- Salt and pepper
- A baking sheet or roasting pan
- An instant-read thermometer
How To Cook Pork Tenderloin In Oven At 350?
To cook a pork tenderloin in the oven at 350 degrees, start by preheating your oven to 350. Then season the pork tenderloin with salt and pepper, or your favorite seasoning blend, and rub it into all sides of the meat. Place the pork on a shallow baking pan, fat-side up.
Cook the pork in the oven for 25 minutes per pound, or until the internal temperature of your meat reaches 145 degrees Fahrenheit. Let the pork rest for 5 minutes before serving.
By following these steps, you’ll be able to enjoy delicious and perfectly cooked pork tenderloin every time!
Watch this video to know how long to cook pork tenderloin in oven at 350.
How Do You Know When Pork Tenderloin Is Done?
To know when your pork tenderloin is done, you’ll need to use a digital thermometer. The internal temperature of your meat should reach 145 degrees Fahrenheit before it’s considered safe to eat.
What To Serve With Baked Pork Tenderloin?
Baked pork tenderloin pairs well with a variety of sides. Some popular options to serve alongside your pork include roasted vegetables, mashed potatoes, macaroni, cheese, or even a salad.
How To Store Oven-Baked Pork Tenderloin?
Any leftover pork tenderloin should be stored in an airtight container in the refrigerator for up to 3 days. If you want to keep it longer, you can also freeze it for up to 3 months.
When reheating cooked pork tenderloin, we recommend doing so in a 350-degree oven until heated through.
More reading: how long bake pork chops 350
Oven-Baked Pork Tenderloin Recipes
Looking for some delicious recipes to make with your oven-baked pork tenderloin? Consider trying out one of these tasty dishes:
- Balsamic Roasted Pork Tenderloin
- Garlic and Herb Crusted Pork Tenderloin
- Honey Mustard Glazed Pork Tenderloin
- Creamy Mustard Pork Tenderloin
No matter how you choose to prepare your pork tenderloin, cooking it in the oven at 350 degrees is a quick and easy way to get a delicious meal on the table!

Conclusion: How Long To Cook Pork Tenderloin In Oven At 350?
Now you know how long to cook pork tenderloin in oven at 350. Cooking pork tenderloin in the oven at 350 degrees can be a great way to enjoy a delicious meal. By following the steps outlined in this article, you’ll be able to enjoy perfectly cooked pork every time. Be sure to use a digital thermometer to check the internal temperature of your meat before serving. Thanks for reading at mollysmtview!
FAQ: Pork Tenderloin
What is the best temperature to cook pork tenderloin?
Get the most flavorful pork tenderloin by cooking it to perfection! Preheat your oven to 350°F and bake until a meat thermometer reads an internal temperature of 150°F. That’s the best way to ensure that you don’t serve up overdone or underdone pork for dinner.
Is it better to cook pork tenderloin fast or slow?
For a succulent pork dinner, opt for flavorful tenderloin over the fattier roasts. Take care not to overcook it – at high heat and with shorter cooking times this lean cut of meat will be juicy and full-flavored if done right.
Should pork tenderloin be baked covered or uncovered?
Make sure you don’t cover the baking dish when preparing your pork tenderloin; use a meat thermometer to monitor its internal temperature. Don’t let overcooking spoil that delicious, juicy taste this lean cut of meat has to offer.
Can I cook a pork tenderloin at 200 degrees?
For succulent pork loin with a smoky flavor, cook it low and slow in your gas smoker at 200-230 degrees. Once the thermometer reads 135-140°F, wrap up that deliciousness in foil to let rest for 10-15 minutes – no worries though as American pork comes free of parasites! To ensure maximum tenderness and juiciness be sure to marinate your meat beforehand with a salt solution.
What is the best method of cooking pork tenderloin?
Transform your pork tenderloin from ordinary to extraordinary by brushing it with additional marinade, then baking it in a preheated oven at 425°F. This high temperature will ensure the meat cooks quickly and doesn’t lose any of its natural flavor or juiciness while reaching a safe internal temperature of 145°F after 15-20 minutes.
What temperature should pork tenderloin be cooked to in Celsius?
To ensure juicy, succulent pork dishes, always cook the meat to an internal temperature of 155°F (68°C). Make sure you take the temperature reading from the thickest part–not touching any bones. Your result will be tender and flavorful!
How long does pork tenderloin take to cook at 225?
Smoke the tenderloins at medium-low heat for up to an hour and a half until they reach 145 degrees F. Transfer them onto a cutting board afterward, allowing about 10 minutes of rest before slicing them into succulent portions that can be served with ease.
How long does it take to cook a pork tenderloin?
Cook up a delicious pork tenderloin like an expert! Preheat your oven to 400 degrees Fahrenheit and sear the meat for optimal flavor. Then, bake it until its internal temperature reaches 145 degrees – usually, 20-25 minutes depending on size. Enjoy perfect results with just one thermometer reading from an instant-read instrument.
Does pork tenderloin get softer the longer it cooks?
For juicy, tender pork – the secret is in how you cook it. Saute your pork to a minimum internal temperature of 145 °F for maximum flavor and texture or use a slow cooker if you want even softer results.
Should you rinse pork tenderloin before cooking?
Instead of washing raw meat and poultry, it’s best to minimize the potential for bacteria cross-contamination by using separate cutting boards or plates when handling these foods. Utilizing proper sanitary techniques will help keep your food safe before you decide to cook it!
Can pork tenderloin be cooked at 350?
A pork tenderloin is a simple dish to make when baked uncovered at 350°F. A general rule of thumb for the cooking time is 20-27 minutes, depending on size and thickness. Enjoy your flavorful entrée!

Bobby Kelly is a bartender at Molly Magees, an Irish pub in Mountain View. He’s been working there for two years and has developed a following among the regulars. Bobby is known for his friendly demeanor and great drink specials. He loves interacting with customers and making them feel welcome. When he’s not at work, Bobby enjoys spending time with his friends and family.